*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Trust Center Verified

Comprehensive analysis of clinical research and evidence*

Hot Flash & Hormone Support By Menopause Science

Hot Flash + Hormone Support is a targeted formula designed to support hormonal regulation and mitigate symptoms associated with estrogen fluctuations.*

View Product

Research Summary

Across these botanicals, menopause-specific trials support reductions in vasomotor symptoms for soy isoflavones, red clover (mixed evidence), and sage; licorice shows a signal for hot flashes in small RCTs; black cohosh evidence is mixed across RCTs and reviews. Dong quai and wild yam have undergone menopause-specific trials, showing no meaningful effect compared to a placebo. For others (e.g., chasteberry), evidence exists in menopausal women, but outcomes can be broader than hot flashes. Where menopause-specific trials don’t exist, we used women-only or mixed-sex human evidence (noted).*

Research at a Glance

Plain Language Summary

The ingredients in Hot Flash Support have been studied for their effects on women’s health, particularly in reducing hot flashes and supporting overall comfort during menopause. Research in menopausal women shows that soy isoflavones, black cohosh, licorice root, red clover, sage leaf, chasteberry, and trans-resveratrol can reduce hot flash frequency or severity, improve symptom scores, or enhance quality of life.

Some ingredients, such as dong quai and red raspberry, have been studied in women or mixed-sex groups for other health benefits. Dong quai, when used as part of a multi-herb formula, has been shown to reduce menstrual pain in women. Red raspberry powder has been shown to improve insulin function, reduce liver insulin resistance, and lower LDL cholesterol in adults at risk for metabolic syndrome.

Other botanicals, like wild yam and blessed thistle, remain included for their traditional use in women’s health, although human trials have not shown proven benefits for menopause or related symptoms.

Key Citations

1. Taku K, et al. Meta-analysis of the effects of soy isoflavones on hot flashes in peri- and postmenopausal women. J Nutr. 2012;142(2):356–364. PMID 22433977

2. Beer AM, et al. Black cohosh in menopausal symptoms – systematic review. Planta Med. 2023;89(9):704–717. PMID 37192826

3. Chen H, et al. Efficacy of Danggui Shaoyao San for primary dysmenorrhea: systematic review and meta-analysis. J Altern Complement Med. 2016;22(7):541–550. PMID 26857875

4. Nahidi F, et al. Licorice root extract in postmenopausal hot flashes: randomized double-blind controlled trial. Iran J Pharm Res. 2013;12(1):217–224. PMID 24250477

5. Baber RJ, et al. Red clover isoflavones for menopausal symptoms. Maturitas. 2021;147:42–50. PMID 33920485

6. Bommer S, et al. Sage in menopausal hot flushes: open-label trial. Adv Ther. 2011;28(6):490–500. PMID 21630133

7. Nazari S, et al. Vitex agnus-castus in menopausal symptom management. J Educ Health Promot. 2019;8:97. PMID 31067851

8. Drugs and Lactation Database (LactMed). Blessed Thistle. 2021. NIH Link

9. Shaughnessy KA, et al. Red raspberry effects on insulin resistance and lipids in adults at risk for metabolic syndrome. J Nutr. 2022;152(6):1438–1449. PMID 35421233

10. Evans HM, et al. Resveratrol in postmenopausal women: randomized trial. Menopause. 2020;27(8):889–898. PMID 32881835
    
    

Tired of Feeling Like a Rotisserie Chicken?

Backed by research on key plant-based compounds. Try Hot Flash & Hormone Support by Menopause Science.

Shop Now

Important Disclaimer

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FTC Disclaimer: Individual results may vary. The research cited represents studies conducted on individual ingredients and may not reflect the specific formulation of this product.